The most commonly used hormonal therapy is tamoxifen, but other therapies are sometimes used
Tamoxifen is an off-label option to treat men for breast cancer, infertility, and idiopathic gynecomastia
It is in a class known as a
Monitoring
Use of high dose tamoxifen in males documented to have hypogonadotropic hypogonadism
SERMs are compounds that exhibit tissue-specific estrogen receptor agonist or antagonist activity
Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men
This SERM has been shown to have some effectiveness against gynecomastia
Medicines used to treat breast cancer and other conditions may be helpful for some adults with gynecomastia
Men with early-stage ER-positive breast cancer who receive adjuvant therapy are usually treated first with tamoxifen
It's for that reason quite crucial to talk about from your physician any kind of health worries
The recurrence rate and mortality in the group of patients without and with tamoxifen treatment were 18
Tamoxifen is used to treat breast cancer in both premenopausal women (women who have not yet gone through the menopause) and postmenopausal women
Due to the lack of prospective data, current treatment of male breast cancer (MBC) is based on information obtained from retrospective analysis or by extrapolation from studies on female patients
A loss of sexual ability/interest may occur in men Tamoxifen is a SERM with tissue-specific agonistic or antagonistic estrogen effects, but in the testis and generally throughout the male reproductive tract, tamoxifen acts as a potent estrogen A typical Nolvadex dosage is between 10 and 40 mg, depending on size, goals and the length of the cycle
To reduce the incidence of breast cancer in women at high risk for breast cancer:
2 Azoospermia is found only in 15%–20% of infertile males, and in 10% with sperm density <1 × 10 6 ml −1
7control vs 1
Use of high dose tamoxifen in males documented to have hypogonadotropic hypogonadism - Fertility and Sterility They concluded that tamoxifen may be effective for the treatment of pubertal gynecomastia and it seems safe to use and randomized controlled studies are necessary to confirm this indication
In men, possible side effects of tamoxifen include :
Tamoxifen alone or in combination with radiation therapy was also used as an adjunct to surgery in the treatment of breast cancer in men at a dosage of 20 mg daily, usually for 1–2 years